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Home - Products - Angiogenesis - EGFR - ZM 323881 hydrochloride

ZM 323881 hydrochloride

CAS No. 193000-39-4

ZM 323881 hydrochloride ( —— )

Catalog No. M13023 CAS No. 193000-39-4

ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor with IC50 of <2 nM, almost no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ZM 323881 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor with IC50 of <2 nM, almost no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.
  • Description
    ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor with IC50 of <2 nM, almost no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR; FGFR1; PDGFRβ; VEGFR1; VEGFR2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    193000-39-4
  • Formula Weight
    411.86
  • Molecular Formula
    C22H19ClFN3O2
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 10 mg/mL (24.28 mM)
  • SMILES
    Cl.CC1=CC(F)=C(NC2=NC=NC3=C2C=CC(OCC2=CC=CC=C2)=C3)C=C1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Whittles CE, et al. Microcirculation, 2002, 9(6), 513-522.
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